Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress

Intracellular pathogens must egress from the host cell to continue their infectious cycle. Apicomplexans are a phylum of intracellular protozoans that have evolved members of the membrane attack complex and perforin (MACPF) family of pore forming proteins to disrupt cellular membranes for traversing...

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Detalles Bibliográficos
Autores principales: Guerra, Alfredo J., Zhang, Ou, Bahr, Constance M. E., Huynh, My-Hang, DelProposto, James, Brown, William C., Wawrzak, Zdzislaw, Koropatkin, Nicole M., Carruthers, Vern B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294395/
https://www.ncbi.nlm.nih.gov/pubmed/30513119
http://dx.doi.org/10.1371/journal.ppat.1007476

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