The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity

Cleavage and polyadenylation (C/P) of mRNA is an important cellular process that promotes increased diversity of mRNA isoforms and could change their stability in different cell types. The cleavage stimulation factor (CstF) complex, part of the C/P machinery, binds to U- and GU-rich sequences locate...

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Detalles Bibliográficos
Autores principales: Grozdanov, Petar N, Masoumzadeh, Elahe, Latham, Michael P, MacDonald, Clinton C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294498/
https://www.ncbi.nlm.nih.gov/pubmed/30257008
http://dx.doi.org/10.1093/nar/gky862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294498/
https://www.ncbi.nlm.nih.gov/pubmed/30257008
http://dx.doi.org/10.1093/nar/gky862

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