Multiple RNA–RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome

The active 3D conformation of the spliceosome's catalytic U2/U6 RNA core is stabilised by a network of secondary and tertiary RNA interactions, but also depends on spliceosomal proteins for its formation. To determine the contribution towards splicing of specific RNA secondary and tertiary inte...

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Detalles Bibliográficos
Autores principales: Bao, Penghui, Boon, Kum-Loong, Will, Cindy L, Hartmuth, Klaus, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294511/
https://www.ncbi.nlm.nih.gov/pubmed/30335160
http://dx.doi.org/10.1093/nar/gky966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294511/
https://www.ncbi.nlm.nih.gov/pubmed/30335160
http://dx.doi.org/10.1093/nar/gky966

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