Multiple RNA–RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome

The active 3D conformation of the spliceosome's catalytic U2/U6 RNA core is stabilised by a network of secondary and tertiary RNA interactions, but also depends on spliceosomal proteins for its formation. To determine the contribution towards splicing of specific RNA secondary and tertiary inte...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Penghui, Boon, Kum-Loong, Will, Cindy L, Hartmuth, Klaus, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294511/
https://www.ncbi.nlm.nih.gov/pubmed/30335160
http://dx.doi.org/10.1093/nar/gky966

Ejemplares similares

Ejemplares similares