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Cooperative translational control of polymorphic BAFF by NF90 and miR-15a

Polymorphisms in untranslated regions (UTRs) of disease-associated mRNAs can alter protein production. We recently identified a genetic variant in the 3′UTR of the TNFSF13B gene, encoding the cytokine BAFF (B-cell-activating factor), that generates an alternative polyadenylation site yielding a shor...

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Detalles Bibliográficos
Autores principales: Idda, M Laura, Lodde, Valeria, McClusky, Waverly G, Martindale, Jennifer L, Yang, Xiaoling, Munk, Rachel, Steri, Maristella, Orrù, Valeria, Mulas, Antonella, Cucca, Francesco, Abdelmohsen, Kotb, Gorospe, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294513/
https://www.ncbi.nlm.nih.gov/pubmed/30272251
http://dx.doi.org/10.1093/nar/gky866