Cargando…

Cooperative translational control of polymorphic BAFF by NF90 and miR-15a

Polymorphisms in untranslated regions (UTRs) of disease-associated mRNAs can alter protein production. We recently identified a genetic variant in the 3′UTR of the TNFSF13B gene, encoding the cytokine BAFF (B-cell-activating factor), that generates an alternative polyadenylation site yielding a shor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Idda, M Laura, Lodde, Valeria, McClusky, Waverly G, Martindale, Jennifer L, Yang, Xiaoling, Munk, Rachel, Steri, Maristella, Orrù, Valeria, Mulas, Antonella, Cucca, Francesco, Abdelmohsen, Kotb, Gorospe, Myriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294513/ https://www.ncbi.nlm.nih.gov/pubmed/30272251 http://dx.doi.org/10.1093/nar/gky866

Ejemplares similares

Survey of senescent cell markers with age in human tissues
por: Idda, M. Laura, et al.
Publicado: (2020)

Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against P. falciparum
por: Lodde, Valeria, et al.
Publicado: (2020)

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif
por: Kuwano, Yuki, et al.
Publicado: (2010)

Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1
por: Panda, Amaresh C., et al.
Publicado: (2017)

Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
por: Yoon, Je-Hyun, et al.
Publicado: (2014)

NF90 modulates processing of a subset of human pri-miRNAs
por: Grasso, Giuseppa, et al.
Publicado: (2020)

HuB and HuD repress telomerase activity by dissociating HuR from TERC
por: Cheng, Xiaolei, et al.
Publicado: (2021)

Prefoldins contribute to maintaining the levels of the spliceosome LSM2–8 complex through Hsp90 in Arabidopsis
por: Esteve-Bruna, David, et al.
Publicado: (2020)

LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR
por: Kim, Jiyoung, et al.
Publicado: (2016)

MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs
por: Sun, Qinyu, et al.
Publicado: (2018)

7SL RNA represses p53 translation by competing with HuR
por: Abdelmohsen, Kotb, et al.
Publicado: (2014)

Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs
por: Abdelmohsen, Kotb, et al.
Publicado: (2011)

Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation
por: Barrera, Aldo, et al.
Publicado: (2020)

WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy
por: Mocciaro, Emanuele, et al.
Publicado: (2023)

TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
por: Chen, Lu, et al.
Publicado: (2022)

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis
por: Panda, Amaresh C., et al.
Publicado: (2016)

A mechanism underlying position-specific regulation of alternative splicing
por: Hamid, Fursham M., et al.
Publicado: (2017)

A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression
por: Goyal, Ashish, et al.
Publicado: (2017)

Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism
por: Scott, Daniel D., et al.
Publicado: (2017)

The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells
por: Ouyang, Huiwu, et al.
Publicado: (2017)

The MRPP1/MRPP2 complex is a tRNA-maturation platform in human mitochondria
por: Reinhard, Linda, et al.
Publicado: (2017)

Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation
por: Bogorad, Andrew M., et al.
Publicado: (2017)

Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide
por: Tang, Leiming, et al.
Publicado: (2017)

Cdk5rap1-mediated 2-methylthio-N(6)-isopentenyladenosine modification is absent from nuclear-derived RNA species
por: Fakruddin, Md., et al.
Publicado: (2017)

The SMAD3 transcription factor binds complex RNA structures with high affinity
por: Dickey, Thayne H., et al.
Publicado: (2017)

An engineered RNA binding protein with improved splicing regulation
por: Hale, Melissa A, et al.
Publicado: (2018)

Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27(Kip1)
por: Roilo, Martina, et al.
Publicado: (2018)

Viewing pre-60S maturation at a minute’s timescale
por: Zisser, Gertrude, et al.
Publicado: (2018)

Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis
por: Shah, Neelam, et al.
Publicado: (2018)

Viral suppressors of RNAi employ a rapid screening mode to discriminate viral RNA from cellular small RNA
por: Fareh, Mohamed, et al.
Publicado: (2018)

Translational regulation by bacterial small RNAs via an unusual Hfq-dependent mechanism
por: Azam, Muhammad S, et al.
Publicado: (2018)

Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli
por: Lalaouna, David, et al.
Publicado: (2018)

Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements
por: Watters, Kyle E, et al.
Publicado: (2018)

RNA-binding specificity landscapes of designer pentatricopeptide repeat proteins elucidate principles of PPR–RNA interactions
por: Miranda, Rafael G, et al.
Publicado: (2018)

Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P
por: Mariotti, Marco, et al.
Publicado: (2017)

Polycytidylation of mitochondrial mRNAs in Chlamydomonas reinhardtii
por: Salinas-Giegé, Thalia, et al.
Publicado: (2017)

Biogenesis and iron-dependency of ribosomal RNA hydroxylation
por: Kimura, Satoshi, et al.
Publicado: (2017)

Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon
por: Basu, Abhijit, et al.
Publicado: (2017)

Distinct roles for the IIId2 sub-domain in pestivirus and picornavirus internal ribosome entry sites
por: Willcocks, Margaret M., et al.
Publicado: (2017)

Tuning RNA folding and function through rational design of junction topology
por: Daher, May, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_76hgegttp5vhkb2l72s91pf8rn