A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation

Programmed DNA double-strand breaks (DSBs) are required for meiotic recombination, but the number is strictly controlled because they are potentially harmful. Here we report a novel protein, Pars11, which is required for Spo11-dependent DSB formation in the protist Tetrahymena. Pars11 localizes to c...

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Detalles Bibliográficos
Autores principales: Tian, Miao, Loidl, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294514/
https://www.ncbi.nlm.nih.gov/pubmed/30357385
http://dx.doi.org/10.1093/nar/gky968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294514/
https://www.ncbi.nlm.nih.gov/pubmed/30357385
http://dx.doi.org/10.1093/nar/gky968

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