Site specific target binding controls RNA cleavage efficiency by the Kaposi's sarcoma-associated herpesvirus endonuclease SOX

A number of viruses remodel the cellular gene expression landscape by globally accelerating messenger RNA (mRNA) degradation. Unlike the mammalian basal mRNA decay enzymes, which largely target mRNA from the 5′ and 3′ end, viruses instead use endonucleases that cleave their targets internally. This...

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Detalles Bibliográficos
Autores principales: Mendez, Aaron S, Vogt, Carolin, Bohne, Jens, Glaunsinger, Britt A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294519/
https://www.ncbi.nlm.nih.gov/pubmed/30321376
http://dx.doi.org/10.1093/nar/gky932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294519/
https://www.ncbi.nlm.nih.gov/pubmed/30321376
http://dx.doi.org/10.1093/nar/gky932

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