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Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs

Meiosis arrest female 1 (MARF1) is a cytoplasmic RNA binding protein that is essential for meiotic progression of mouse oocytes, in part by limiting retrotransposon expression. MARF1 is also expressed in somatic cells and tissues; however, its mechanism of action has yet to be investigated. Human MA...

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Detalles Bibliográficos
Autores principales: Nishimura, Tamiko, Fakim, Hana, Brandmann, Tobias, Youn, Ji-Young, Gingras, Anne-Claude, Jinek, Martin, Fabian, Marc R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294520/
https://www.ncbi.nlm.nih.gov/pubmed/30364987
http://dx.doi.org/10.1093/nar/gky1011