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Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs
Meiosis arrest female 1 (MARF1) is a cytoplasmic RNA binding protein that is essential for meiotic progression of mouse oocytes, in part by limiting retrotransposon expression. MARF1 is also expressed in somatic cells and tissues; however, its mechanism of action has yet to be investigated. Human MA...
Autores principales: | Nishimura, Tamiko, Fakim, Hana, Brandmann, Tobias, Youn, Ji-Young, Gingras, Anne-Claude, Jinek, Martin, Fabian, Marc R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294520/ https://www.ncbi.nlm.nih.gov/pubmed/30364987 http://dx.doi.org/10.1093/nar/gky1011 |
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