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The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Zα DNA-binding activity

The Z-DNA binding domain (Zα), derived from the human RNA editing enzyme ADAR1, can induce and stabilize the Z-DNA conformation. However, the biological function of Zα/Z-DNA remains elusive. Herein, we sought to identify proteins associated with Zα to gain insight into the functional network of Zα/Z...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Hua, Shih, Yan-Ping, Ho, Meng-Ru, Wang, Andrew H-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294567/
https://www.ncbi.nlm.nih.gov/pubmed/30304469
http://dx.doi.org/10.1093/nar/gky933