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Aging-Related Calcium Dysregulation in Rat Entorhinal Neurons Homologous with the Human Entorhinal Neurons in which Alzheimer’s Disease Neurofibrillary Tangles First Appear

Aging is the leading risk factor for idiopathic Alzheimer’s disease (AD), indicating that normal aging processes promote AD and likely are present in the neurons in which AD pathogenesis originates. In AD, neurofibrillary tangles (NFTs) appear first in entorhinal cortex, implying that aging processe...

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Detalles Bibliográficos
Autores principales: Gant, John C., Kadish, Inga, Chen, Kuey-Chu, Thibault, Olivier, Blalock, Eric M., Porter, Nada M., Landfield, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294592/
https://www.ncbi.nlm.nih.gov/pubmed/30412490
http://dx.doi.org/10.3233/JAD-180618