S1P(1) receptor phosphorylation, internalization, and interaction with Rab proteins: effects of sphingosine 1-phosphate, FTY720-P, phorbol esters, and paroxetine

Sphingosine 1-phosphate (S1P) and FTY720-phosphate (FTYp) increased intracellular calcium in cells expressing S1P(1) mCherry-tagged receptors; the synthetic agonist was considerably less potent. Activation of protein kinase C by phorbol myristate acetate (PMA) blocked these effects. The three agents...

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Detalles Bibliográficos
Autores principales: Martínez-Morales, Juan Carlos, Romero-Ávila, M. Teresa, Reyes-Cruz, Guadalupe, García-Sáinz, J. Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294635/
https://www.ncbi.nlm.nih.gov/pubmed/30366961
http://dx.doi.org/10.1042/BSR20181612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294635/
https://www.ncbi.nlm.nih.gov/pubmed/30366961
http://dx.doi.org/10.1042/BSR20181612

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