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Hippo signaling dysfunction induces cancer cell addiction to YAP
Over the past decades, the Hippo has been established as a crucial pathway involved in organ size control and cancer suppression. Dysregulation of Hippo signaling and hyperactivation of its downstream effector YAP are frequently associated with various human cancers. However, the underlying signific...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294669/ https://www.ncbi.nlm.nih.gov/pubmed/30068939 http://dx.doi.org/10.1038/s41388-018-0419-5 |