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Hippo signaling dysfunction induces cancer cell addiction to YAP

Over the past decades, the Hippo has been established as a crucial pathway involved in organ size control and cancer suppression. Dysregulation of Hippo signaling and hyperactivation of its downstream effector YAP are frequently associated with various human cancers. However, the underlying signific...

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Detalles Bibliográficos
Autores principales: Han, Han, Yang, Bing, Nakaoka, Hiroki J, Yang, Jiadong, Zhao, Yifan, Le Nguyen, Kathern, Bishara, Amell Taffy, Mandalia, Tejas Krishen, Wang, Wenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294669/
https://www.ncbi.nlm.nih.gov/pubmed/30068939
http://dx.doi.org/10.1038/s41388-018-0419-5

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