Transcription Factor Levels after Forward Programming of Human Pluripotent Stem Cells with GATA1, FLI1, and TAL1 Determine Megakaryocyte versus Erythroid Cell Fate Decision

The production of blood cells and their precursors from human pluripotent stem cells (hPSCs) in vitro has the potential to make a significant impact upon healthcare provision. We demonstrate that the forward programming of hPSCs through overexpression of GATA1, FLI1, and TAL1 leads to the production...

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Detalles Bibliográficos
Autores principales: Dalby, Amanda, Ballester-Beltrán, Jose, Lincetto, Chiara, Mueller, Annett, Foad, Nicola, Evans, Amanda, Baye, James, Turro, Ernest, Moreau, Thomas, Tijssen, Marloes R., Ghevaert, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294717/
https://www.ncbi.nlm.nih.gov/pubmed/30503262
http://dx.doi.org/10.1016/j.stemcr.2018.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294717/
https://www.ncbi.nlm.nih.gov/pubmed/30503262
http://dx.doi.org/10.1016/j.stemcr.2018.11.001

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