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GSK3β negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons

Translin-associated protein X (TRAX) is a scaffold protein with various functions and has been associated with mental illnesses, including schizophrenia. We have previously demonstrated that TRAX interacts with a Gsα protein-coupled receptor, the A(2A) adenosine receptor (A(2A)R), and mediates the f...

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Detalles Bibliográficos
Autores principales: Chien, Ting, Weng, Yu-Ting, Chang, Shu-Yung, Lai, Hsing-Lin, Chiu, Feng-Lan, Kuo, Hung-Chih, Chuang, De-Maw, Chern, Yijuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294740/
https://www.ncbi.nlm.nih.gov/pubmed/29298990
http://dx.doi.org/10.1038/s41380-017-0007-z