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GSK3β negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons
Translin-associated protein X (TRAX) is a scaffold protein with various functions and has been associated with mental illnesses, including schizophrenia. We have previously demonstrated that TRAX interacts with a Gsα protein-coupled receptor, the A(2A) adenosine receptor (A(2A)R), and mediates the f...
Autores principales: | Chien, Ting, Weng, Yu-Ting, Chang, Shu-Yung, Lai, Hsing-Lin, Chiu, Feng-Lan, Kuo, Hung-Chih, Chuang, De-Maw, Chern, Yijuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294740/ https://www.ncbi.nlm.nih.gov/pubmed/29298990 http://dx.doi.org/10.1038/s41380-017-0007-z |
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