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Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice
Cytoglobin (CYGB), discovered in hepatic stellate cells (HSCs), is known to possess a radical scavenger function, but its pathophysiological roles remain unclear. Here, for the first time, we generated a new transgenic (TG) mouse line in which both Cygb and mCherry reporter gene expression were unde...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294752/ https://www.ncbi.nlm.nih.gov/pubmed/30552362 http://dx.doi.org/10.1038/s41598-018-36215-4 |