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Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice

Cytoglobin (CYGB), discovered in hepatic stellate cells (HSCs), is known to possess a radical scavenger function, but its pathophysiological roles remain unclear. Here, for the first time, we generated a new transgenic (TG) mouse line in which both Cygb and mCherry reporter gene expression were unde...

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Detalles Bibliográficos
Autores principales: Thi Thanh Hai, Nguyen, Thuy, Le Thi Thanh, Shiota, Akira, Kadono, Chiho, Daikoku, Atsuko, Hoang, Dinh Viet, Dat, Ninh Quoc, Sato-Matsubara, Misako, Yoshizato, Katsutoshi, Kawada, Norifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294752/
https://www.ncbi.nlm.nih.gov/pubmed/30552362
http://dx.doi.org/10.1038/s41598-018-36215-4