The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans

Programmed cell death, which occurs through a conserved core molecular pathway, is important for fundamental developmental and homeostatic processes. The human iron–sulfur binding protein NAF-1/CISD2 binds to Bcl-2 and its disruption in cells leads to an increase in apoptosis. Other members of the C...

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Detalles Bibliográficos
Autores principales: King, Skylar D., Gray, Chipo F., Song, Luhua, Nechushtai, Rachel, Gumienny, Tina L., Mittler, Ron, Padilla, Pamela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294797/
https://www.ncbi.nlm.nih.gov/pubmed/29666474
http://dx.doi.org/10.1038/s41418-018-0108-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294797/
https://www.ncbi.nlm.nih.gov/pubmed/29666474
http://dx.doi.org/10.1038/s41418-018-0108-5

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