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TLR2/4-mediated NF-κB pathway combined with the histone modification regulates β-defensins and interleukins expression by sodium phenyl butyrate in porcine intestinal epithelial cells

BACKGROUND: Host defense peptides (HDPs) possess direct antibacterial, antineoplastic, and immunomodulatory abilities, playing a vital role in innate immunity. Dietary-regulated HDP holds immense potential as a novel pathway for preventing infection. OBJECTIVE: In this study, we examined the regulat...

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Detalles Bibliográficos
Autores principales: Dou, Xiujing, Han, Junlan, Ma, Qiuyuan, Cheng, Baojing, Shan, Anshan, Gao, Nan, Yang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Academia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294838/
https://www.ncbi.nlm.nih.gov/pubmed/30574051
http://dx.doi.org/10.29219/fnr.v62.1493