Structural snapshots of OxyR reveal the peroxidatic mechanism of H(2)O(2) sensing

Hydrogen peroxide (H(2)O(2)) is a strong oxidant capable of oxidizing cysteinyl thiolates, yet only a few cysteine-containing proteins have exceptional reactivity toward H(2)O(2). One such example is the prokaryotic transcription factor OxyR, which controls the antioxidant response in bacteria, and...

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Detalles Bibliográficos
Autores principales: Pedre, Brandán, Young, David, Charlier, Daniel, Mourenza, Álvaro, Rosado, Leonardo Astolfi, Marcos-Pascual, Laura, Wahni, Khadija, Martens, Edo, G. de la Rubia, Alfonso, Belousov, Vsevolod V., Mateos, Luis M., Messens, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294878/
https://www.ncbi.nlm.nih.gov/pubmed/30463959
http://dx.doi.org/10.1073/pnas.1807954115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294878/
https://www.ncbi.nlm.nih.gov/pubmed/30463959
http://dx.doi.org/10.1073/pnas.1807954115

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