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Structural snapshots of OxyR reveal the peroxidatic mechanism of H(2)O(2) sensing
Hydrogen peroxide (H(2)O(2)) is a strong oxidant capable of oxidizing cysteinyl thiolates, yet only a few cysteine-containing proteins have exceptional reactivity toward H(2)O(2). One such example is the prokaryotic transcription factor OxyR, which controls the antioxidant response in bacteria, and...
Autores principales: | Pedre, Brandán, Young, David, Charlier, Daniel, Mourenza, Álvaro, Rosado, Leonardo Astolfi, Marcos-Pascual, Laura, Wahni, Khadija, Martens, Edo, G. de la Rubia, Alfonso, Belousov, Vsevolod V., Mateos, Luis M., Messens, Joris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294878/ https://www.ncbi.nlm.nih.gov/pubmed/30463959 http://dx.doi.org/10.1073/pnas.1807954115 |
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