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Structure and architecture of immature and mature murine leukemia virus capsids

Retroviruses assemble and bud from infected cells in an immature form and require proteolytic maturation for infectivity. The CA (capsid) domains of the Gag polyproteins assemble a protein lattice as a truncated sphere in the immature virion. Proteolytic cleavage of Gag induces dramatic structural r...

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Detalles Bibliográficos
Autores principales: Qu, Kun, Glass, Bärbel, Doležal, Michal, Schur, Florian K. M., Murciano, Brice, Rein, Alan, Rumlová, Michaela, Ruml, Tomáš, Kräusslich, Hans-Georg, Briggs, John A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294937/
https://www.ncbi.nlm.nih.gov/pubmed/30478053
http://dx.doi.org/10.1073/pnas.1811580115