Cargando…

Structure and architecture of immature and mature murine leukemia virus capsids

Retroviruses assemble and bud from infected cells in an immature form and require proteolytic maturation for infectivity. The CA (capsid) domains of the Gag polyproteins assemble a protein lattice as a truncated sphere in the immature virion. Proteolytic cleavage of Gag induces dramatic structural r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Kun, Glass, Bärbel, Doležal, Michal, Schur, Florian K. M., Murciano, Brice, Rein, Alan, Rumlová, Michaela, Ruml, Tomáš, Kräusslich, Hans-Georg, Briggs, John A. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294937/ https://www.ncbi.nlm.nih.gov/pubmed/30478053 http://dx.doi.org/10.1073/pnas.1811580115

Ejemplares similares

High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation
por: Mattei, Simone, et al.
Publicado: (2018)

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses
por: Dodonova, Svetlana O., et al.
Publicado: (2019)

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
por: Davidsson, Marcus, et al.
Publicado: (2019)

Grammar of protein domain architectures
por: Yu, Lijia, et al.
Publicado: (2019)

Sensorimotor brain dynamics reflect architectural affordances
por: Djebbara, Zakaria, et al.
Publicado: (2019)

The constrained architecture of mammalian Hox gene clusters
por: Darbellay, Fabrice, et al.
Publicado: (2019)

The genetic architecture of teosinte catalyzed and constrained maize domestication
por: Yang, Chin Jian, et al.
Publicado: (2019)

Prostaglandin signaling regulates renal multiciliated cell specification and maturation
por: Marra, Amanda N., et al.
Publicado: (2019)

Crystal growth kinetics as an architectural constraint on the evolution of molluscan shells
por: Schoeppler, Vanessa, et al.
Publicado: (2019)

Profiling proliferative cells and their progeny in damaged murine hearts
por: Kretzschmar, Kai, et al.
Publicado: (2018)

Connectional architecture of a mouse hypothalamic circuit node controlling social behavior
por: Lo, Liching, et al.
Publicado: (2019)

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr
por: Zakany, Jozsef, et al.
Publicado: (2017)

Differential cortical microstructural maturation in the preterm human brain with diffusion kurtosis and tensor imaging
por: Ouyang, Minhui, et al.
Publicado: (2019)

Transcriptomic analysis of field-droughted sorghum from seedling to maturity reveals biotic and metabolic responses
por: Varoquaux, Nelle, et al.
Publicado: (2019)

Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis
por: Andreatta, Gabriele, et al.
Publicado: (2020)

Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity
por: Zanos, Theodoros P., et al.
Publicado: (2018)

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor
por: Nelson, Christopher A., et al.
Publicado: (2018)

Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth
por: Spoljaric, Albert, et al.
Publicado: (2017)

Multifunctionalized hydrogels foster hNSC maturation in 3D cultures and neural regeneration in spinal cord injuries
por: Marchini, Amanda, et al.
Publicado: (2019)

Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during Drosophila wing morphogenesis
por: Gui, Jinghua, et al.
Publicado: (2019)

Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response
por: Lou, Jieqiong, et al.
Publicado: (2019)

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay
por: Nguyen, Andrew D., et al.
Publicado: (2018)

Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation
por: Yan, Qi, et al.
Publicado: (2018)

High-resolution contrast-enhanced microCT reveals the true three-dimensional morphology of the murine placenta
por: De Clercq, Katrien, et al.
Publicado: (2019)

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination
por: McMurran, Christopher E., et al.
Publicado: (2019)

Sleep–wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex
por: Hor, Charlotte N., et al.
Publicado: (2019)

PDGFRα(+) pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
por: Greicius, Gediminas, et al.
Publicado: (2018)

Polysialic acid is a cellular receptor for human adenovirus 52
por: Lenman, Annasara, et al.
Publicado: (2018)

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages
por: Carlin, Aaron F., et al.
Publicado: (2018)

Weak warning signals can persist in the absence of gene flow
por: Lawrence, J. P., et al.
Publicado: (2019)

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs
por: Oberhofer, Georg, et al.
Publicado: (2018)

Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive
por: Oberhofer, Georg, et al.
Publicado: (2019)

BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
por: Li, Andrew G., et al.
Publicado: (2018)

On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations
por: Yang, Xiaoting, et al.
Publicado: (2018)

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages
por: Muse, Evan D., et al.
Publicado: (2018)

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
por: Zannas, Anthony S., et al.
Publicado: (2019)

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk
por: Hlusko, Leslea J., et al.
Publicado: (2018)

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction
por: Hillig, Roman C., et al.
Publicado: (2019)

Activated integrins identify functional antigen-specific CD8(+) T cells within minutes after antigen stimulation
por: Dimitrov, Stoyan, et al.
Publicado: (2018)

Leptin signaling impairs macrophage defenses against Salmonella Typhimurium
por: Fischer, Julia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qms6t3660ninjn9cu2rl42d9hq