Molecular structure of the ATP-bound, phosphorylated human CFTR

The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel important in maintaining proper functions of the lung, pancreas, and intestine. The activity of CFTR is regulated by ATP and protein kinase A-dependent phosphorylation. To understand the conformational changes elicite...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Liu, Fangyu, Chen, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294961/
https://www.ncbi.nlm.nih.gov/pubmed/30459277
http://dx.doi.org/10.1073/pnas.1815287115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294961/
https://www.ncbi.nlm.nih.gov/pubmed/30459277
http://dx.doi.org/10.1073/pnas.1815287115

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