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Preparation of lyophilized recombinant prion protein for TSE diagnosis by RT-QuIC
OBJECTIVE: Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases, often referred as prion diseases. TSEs result from the misfolding of the cellular prion protein (PrP(C)) into a pathogenic form (PrP(Sc)) that accumulates in the brain and lymphatic tissue. A...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295004/ https://www.ncbi.nlm.nih.gov/pubmed/30547851 http://dx.doi.org/10.1186/s13104-018-3982-5 |