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C-Src confers resistance to mitotic stress through inhibition DMAP1/Bub3 complex formation in pancreatic cancer

BACKGROUND: Chromatin modification at mitosis is closely related to transcriptional reactivation in the subsequent cell cycle. We reasoned this process is deregulated by oncogenic signals, which would contribute to mitotic stress resistance in pancreatic cancer. Here, we show DMAP1/Bub3 complex medi...

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Detalles Bibliográficos
Autores principales: Li, Jingjie, Hu, Bin, Wang, Ting, Huang, Wenhua, Ma, Chunmin, Zhao, Qin, Zhuo, Lingang, Zhang, Tao, Jiang, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295060/
https://www.ncbi.nlm.nih.gov/pubmed/30553276
http://dx.doi.org/10.1186/s12943-018-0919-5