Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a major health burden in need for new medication. To identify potential drug targets a genomic study was performed in lipid-laden primary human hepatocyte (PHH) and human hepatoma cell cultures. METHODS: PHH, HuH7 and HepG2 hepatoma cell cultu...

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Detalles Bibliográficos
Autores principales: Breher-Esch, Stephanie, Sahini, Nishika, Trincone, Anna, Wallstab, Christin, Borlak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295111/
https://www.ncbi.nlm.nih.gov/pubmed/30547786
http://dx.doi.org/10.1186/s12920-018-0438-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295111/
https://www.ncbi.nlm.nih.gov/pubmed/30547786
http://dx.doi.org/10.1186/s12920-018-0438-7

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