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Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a major health burden in need for new medication. To identify potential drug targets a genomic study was performed in lipid-laden primary human hepatocyte (PHH) and human hepatoma cell cultures. METHODS: PHH, HuH7 and HepG2 hepatoma cell cultu...

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Detalles Bibliográficos
Autores principales:	Breher-Esch, Stephanie, Sahini, Nishika, Trincone, Anna, Wallstab, Christin, Borlak, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295111/ https://www.ncbi.nlm.nih.gov/pubmed/30547786 http://dx.doi.org/10.1186/s12920-018-0438-7

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