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Multilayered gene control drives timely exit from the stem cell state in uncommitted progenitors during Drosophila asymmetric neural stem cell division

Self-renewal genes maintain stem cells in an undifferentiated state by preventing the commitment to differentiate. Robust inactivation of self-renewal gene activity following asymmetric stem cell division allows uncommitted stem cell progeny to exit from an undifferentiated state and initiate the co...

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Detalles Bibliográficos
Autores principales: Komori, Hideyuki, Golden, Krista L., Kobayashi, Taeko, Kageyama, Ryoichiro, Lee, Cheng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295162/
https://www.ncbi.nlm.nih.gov/pubmed/30463902
http://dx.doi.org/10.1101/gad.320333.118