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BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

Human globin gene production transcriptionally “switches” from fetal to adult synthesis shortly after birth and is controlled by macromolecular complexes that enhance or suppress transcription by cis elements scattered throughout the locus. The DRED (direct repeat erythroid-definitive) repressor is...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Jearawiriyapaisarn, Natee, Lee, Mary P., Hosoya, Tomonori, Wu, Qingqing, Myers, Greggory, Lim, Kim-Chew, Kurita, Ryo, Nakamura, Yukio, Vojtek, Anne B., Rual, Jean-François, Engel, James Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295165/
https://www.ncbi.nlm.nih.gov/pubmed/30463901
http://dx.doi.org/10.1101/gad.318436.118