Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells

Genomic imprinting is essential for mammalian development. Recent studies have revealed that maternal histone H3 Lys27 trimethylation (H3K27me3) can mediate DNA methylation-independent genomic imprinting. However, the regulatory mechanisms and functions of this new imprinting mechanism are largely u...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoue, Azusa, Chen, Zhiyuan, Yin, Qiangzong, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295166/
https://www.ncbi.nlm.nih.gov/pubmed/30463900
http://dx.doi.org/10.1101/gad.318675.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295166/
https://www.ncbi.nlm.nih.gov/pubmed/30463900
http://dx.doi.org/10.1101/gad.318675.118

Ejemplares similares