Cargando…
Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells
Genomic imprinting is essential for mammalian development. Recent studies have revealed that maternal histone H3 Lys27 trimethylation (H3K27me3) can mediate DNA methylation-independent genomic imprinting. However, the regulatory mechanisms and functions of this new imprinting mechanism are largely u...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295166/ https://www.ncbi.nlm.nih.gov/pubmed/30463900 http://dx.doi.org/10.1101/gad.318675.118 |