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Evolution of aneuploidy: overcoming the original CIN
Chromosomal instability (CIN) generates continuously novel aneuploid genomes—unbalanced chromosome combinations that differ from the haploid chromosome set and its multiples. On one hand, this causes problems for cells, as high CIN and aneuploidy impair cellular proliferation by inducing multiple ce...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295170/ https://www.ncbi.nlm.nih.gov/pubmed/30509947 http://dx.doi.org/10.1101/gad.321810.118 |