Cargando…

Co-repressor, co-activator and general transcription factor: the many faces of the Sin3 histone deacetylase (HDAC) complex

At face value, the Sin3 histone deacetylase (HDAC) complex appears to be a prototypical co-repressor complex, that is, a multi-protein complex recruited to chromatin by DNA bound repressor proteins to facilitate local histone deacetylation and transcriptional repression. While this is almost certain...

Descripción completa

Detalles Bibliográficos
Autores principales: Adams, Grace E., Chandru, Aditya, Cowley, Shaun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295471/
https://www.ncbi.nlm.nih.gov/pubmed/30552170
http://dx.doi.org/10.1042/BCJ20170314