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The in vivo dsRNA Cleavage Has Sequence Preference in Insects
Exogenous dsRNA enters the insect body and can induce the RNAi effect only when it is cleaved into siRNA. However, what kinds of base composition are easier to cut and what kinds of siRNA will be produced in vivo is largely unknown. In this study, we found that dsRNA processing into siRNA has sequen...
Autores principales: | Guan, Ruobing, Hu, Shaoru, Li, Haichao, Shi, Zhenying, Miao, Xuexia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295558/ https://www.ncbi.nlm.nih.gov/pubmed/30618790 http://dx.doi.org/10.3389/fphys.2018.01768 |
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