Immunosuppression in Experimental Chagas Disease Is Mediated by an Alteration of Bone Marrow Stromal Cell Function During the Acute Phase of Infection

After infection with Trypanosoma cruzi, the etiologic agent of Chagas disease, immunosuppression, and apoptosis of mature lymphocytes contribute to the establishment of the parasite in the host and thereby to persistence and pathology in the chronic stage of infection. In a systemic mouse model of e...

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Detalles Bibliográficos
Autores principales: Müller, Uwe, Schaub, Günter A., Mossmann, Horst, Köhler, Gabriele, Carsetti, Rita, Hölscher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295583/
https://www.ncbi.nlm.nih.gov/pubmed/30619242
http://dx.doi.org/10.3389/fimmu.2018.02794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295583/
https://www.ncbi.nlm.nih.gov/pubmed/30619242
http://dx.doi.org/10.3389/fimmu.2018.02794

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