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The role of cytochrome P450 2E1 on ethanol-mediated oxidative stress and HIV replication in human monocyte-derived macrophages

BACKGROUND: Alcohol consumption is considered to be a major health problem among people living with HIV/AIDS. Our previous reports have shown that ethanol reduced intracellular concentrations of antiretroviral drugs elvitegravir and darunavir in the HIV-1-infected U1 cell line. Ethanol also increase...

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Detalles Bibliográficos
Autores principales: Gong, Yuqing, Rao, P.S.S., Sinha, Namita, Ranjit, Sabina, Cory, Theodore J., Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295597/
https://www.ncbi.nlm.nih.gov/pubmed/30582009
http://dx.doi.org/10.1016/j.bbrep.2018.11.008