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Upregulated SK2 Expression and Impaired CaMKII Phosphorylation Are Shared Synaptic Defects Between 16p11.2del and 129S:Δdisc1 Mutant Mice

Ion channel gating and kinase regulation of N-methyl-D-aspartate receptor 1 activity are fundamental mechanisms that govern synaptic plasticity. In this study, we showed that two mutant models (16p11.2del and Δdisc1) that recapitulate aspects of human cognitive disorders shared a similar defect in N...

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Detalles Bibliográficos
Autores principales: Sultana, Razia, Ghandi, Tanya, M. Davila, Alexandra, Lee, Charles C., Ogundele, Olalekan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295693/
https://www.ncbi.nlm.nih.gov/pubmed/33592687
http://dx.doi.org/10.1177/1759091418817641