SphK1/S1P mediates TGF-β1-induced proliferation of pulmonary artery smooth muscle cells and its potential mechanisms

The upregulation of Sphingosine kinase 1 (SphK1) expression and accompanied sphingosine-1-phosphate (S1P) production have been reported to contribute to the proliferation of pulmonary artery smooth muscle cells (PASMC) and pulmonary arterial remodeling. However, the molecular mechanisms of SphK1/S1P...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Feng, Wei, Li, Fangwei, Shi, Wenhua, Zhai, Cui, Li, Shaojun, Zhu, Yanting, Yan, Xin, Wang, Qingting, Liu, Lu, Xie, Xinming, Li, Manxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295694/
https://www.ncbi.nlm.nih.gov/pubmed/30430898
http://dx.doi.org/10.1177/2045894018816977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295694/
https://www.ncbi.nlm.nih.gov/pubmed/30430898
http://dx.doi.org/10.1177/2045894018816977

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