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Apalutamide in the treatment of castrate-resistant prostate cancer: evidence from clinical trials

Apalutamide (ARN-509) is a second-generation androgen receptor (AR) antagonist that was developed to inhibit AR-mediated prostate cancer cell proliferation. Following the initial promising clinical efficacy results in phase I and II clinical trials of patients with metastatic castrate-resistant pros...

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Detalles Bibliográficos
Autores principales: Koshkin, Vadim S., Small, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295778/
https://www.ncbi.nlm.nih.gov/pubmed/30574205
http://dx.doi.org/10.1177/1756287218811450