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Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale

[Image: see text] Proteins fold into a single structural ensemble but can also misfold into many diverse structures including small aggregates and fibrils, which differ in their toxicity. The aggregate surface properties play an important role in how they interact with the plasma membrane and cellul...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Eun, Sang, Jason C., Rodrigues, Margarida, Carr, Alexander R., Horrocks, Mathew H., De, Suman, Bongiovanni, Marie N., Flagmeier, Patrick, Dobson, Christopher M., Wales, David J., Lee, Steven F., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295917/
https://www.ncbi.nlm.nih.gov/pubmed/30380895
http://dx.doi.org/10.1021/acs.nanolett.8b02916