Reframing gene essentiality in terms of adaptive flexibility

BACKGROUND: Essentiality assays are important tools commonly utilized for the discovery of gene functions. Growth/no growth screens of single gene knockout strain collections are also often utilized to test the predictive power of genome-scale models. False positive predictions occur when computatio...

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Detalles Bibliográficos
Autores principales: Guzmán, Gabriela I., Olson, Connor A., Hefner, Ying, Phaneuf, Patrick V., Catoiu, Edward, Crepaldi, Lais B., Micas, Lucas Goldschmidt, Palsson, Bernhard O., Feist, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296033/
https://www.ncbi.nlm.nih.gov/pubmed/30558585
http://dx.doi.org/10.1186/s12918-018-0653-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296033/
https://www.ncbi.nlm.nih.gov/pubmed/30558585
http://dx.doi.org/10.1186/s12918-018-0653-z

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