Cargando…

Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer

BACKGROUND: FGD4 (Frabin) is an F-actin binding protein with GTP/GDP exchange activity specific for CDC42. It is involved in reorganization of the actin cytoskeleton, which requires both actin binding and CDC42 activating function of FGD4. Expression of FGD4 is altered in patients with heterogeneous...

Descripción completa

Detalles Bibliográficos
Autores principales: Bossan, Alexia, Ottman, Richard, Andl, Thomas, Hasan, Md Faqrul, Mahajan, Nupam, Coppola, Domenico, Chakrabarti, Ratna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296060/
https://www.ncbi.nlm.nih.gov/pubmed/30558664
http://dx.doi.org/10.1186/s12885-018-5096-9