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Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer
BACKGROUND: FGD4 (Frabin) is an F-actin binding protein with GTP/GDP exchange activity specific for CDC42. It is involved in reorganization of the actin cytoskeleton, which requires both actin binding and CDC42 activating function of FGD4. Expression of FGD4 is altered in patients with heterogeneous...
Autores principales: | Bossan, Alexia, Ottman, Richard, Andl, Thomas, Hasan, Md Faqrul, Mahajan, Nupam, Coppola, Domenico, Chakrabarti, Ratna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296060/ https://www.ncbi.nlm.nih.gov/pubmed/30558664 http://dx.doi.org/10.1186/s12885-018-5096-9 |
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