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Methods in the design and implementation of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial

BACKGROUND: Few papers discuss the pragmatics of conducting large, cluster randomized clinical trials. Here we describe the sequential steps taken to develop methods to implement the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) trial that tested the effect of a nurse...

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Detalles Bibliográficos
Autores principales: Curley, Martha A. Q., Gedeit, Rainer G., Dodson, Brenda L, Amling, June K., Soetenga, Deborah J., Corriveau, Christiane O., Asario, Lisa A., Wypij, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296093/
https://www.ncbi.nlm.nih.gov/pubmed/30558653
http://dx.doi.org/10.1186/s13063-018-3075-8