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Monitoring HIV DNA and cellular activation markers in HIV-infected humanized mice under cART

BACKGROUND: The major obstacle to cure of HIV type-1 infection is the presence of the HIV reservoir, hidden from the immune system and insensitive to combined antiretroviral therapy (cART). Eradication approaches have been hindered by the difficulty for accurately monitoring its size in vivo, especi...

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Detalles Bibliográficos
Autores principales: Rochat, Mary-Aude, Schlaepfer, Erika, Kuster, Stefan P., Li, Duo, Audige, Annette, Ivic, Sandra, Fahrny, Audrey, Speck, Roberto F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296118/
https://www.ncbi.nlm.nih.gov/pubmed/30558630
http://dx.doi.org/10.1186/s12985-018-1101-9