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The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

BACKGROUND: Different cell types possess different copies of mtDNA to support their specific requirements for cellular metabolism. Cell-specific mtDNA copy numbers are established through cell-specific mtDNA replication during cell differentiation. However, cancer cells are trapped in a “pseudo-diff...

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Detalles Bibliográficos
Autores principales: Sun, Xin, Vaghjiani, Vijesh, Jayasekara, W. Samantha N., Cain, Jason E., St. John, Justin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296150/
https://www.ncbi.nlm.nih.gov/pubmed/30558637
http://dx.doi.org/10.1186/s13148-018-0590-0