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The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma
BACKGROUND: Different cell types possess different copies of mtDNA to support their specific requirements for cellular metabolism. Cell-specific mtDNA copy numbers are established through cell-specific mtDNA replication during cell differentiation. However, cancer cells are trapped in a “pseudo-diff...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296150/ https://www.ncbi.nlm.nih.gov/pubmed/30558637 http://dx.doi.org/10.1186/s13148-018-0590-0 |