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Topical anesthesia therapy using lidocaine-loaded nanostructured lipid carriers: tocopheryl polyethylene glycol 1000 succinate-modified transdermal delivery system

PURPOSE: Transdermal drug delivery of local anesthetics using lipid nanoparticles could enhance lipophilic drugs permeation through the stratum corneum, improve drug diffusion to deeper skin, and exert good therapeutic effects. The purpose of this study was to engineer a Tocopheryl Polyethylene Glyc...

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Detalles Bibliográficos
Autores principales: Zhao, Xiangju, Sun, Ying, Li, Zhaoguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296185/
https://www.ncbi.nlm.nih.gov/pubmed/30587919
http://dx.doi.org/10.2147/DDDT.S187177